Consistent Changes in Gut Bacteria and Their Functions in Major Depression

Major depressive disorder (MDD) is associated with gut microbiome alterations.

• There is growing evidence linking MDD to changes in gut bacteria.
• Published findings on gut microbiome alterations in MDD are inconsistent.
• This review evaluates differences in gut microbiome composition and function between MDD patients and healthy individuals.
• The goal is to identify reproducible microbial patterns associated with depression.

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