Medical sciences (Basel, Switzerland)

Changes in Gut Bacteria and Gut-Brain Communication Linked to Addiction

Updated

Abstract

Chronic substance use may disrupt gut microbiota composition and function.

  • Disruption of gut microbiota is associated with intestinal dysfunction.
  • Changes in gut microbiota may contribute to systemic inflammation.
  • Gut-brain axis dysregulation is linked to alterations in microbial composition.
  • Current evidence is fragmented, focusing on individual substances rather than overall patterns.
  • There is a lack of substance-specific microbial signatures in existing studies.

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