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Gut Microbiota and Polycystic Ovary Syndrome (PCOS): Understanding the Pathogenesis and the Role of Probiotics as a Therapeutic Strategy
Gut Bacteria and Polycystic Ovary Syndrome: How They Are Linked and the Potential Benefits of Probiotics
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Abstract
Women with polycystic ovary syndrome (PCOS) show higher numbers of specific gut bacteria like Porphyromonas spp., B. coprophilus, and F. prausnitzii.
- High insulin resistance, hyperandrogenism, irregular periods, and infertility are common in women with PCOS.
- Dysbiosis of the gut microbiota is observed in women with PCOS compared to healthy individuals.
- Bacteria that produce short-chain fatty acids (SCFAs) are less abundant in the guts of women with PCOS.
- SCFAs play a role in regulating metabolic activities and may help reduce insulin resistance.
- Probiotic supplements may improve the condition of women with PCOS by enhancing gut microbiome diversity and increasing SCFA production.
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