Common and condition-specific gut bacteria changes in older adults with depression and constipation

Constipation and depression frequently co-occur in older adults.

• Gut microbiota dysbiosis may be a shared feature of both constipation and depression.
• The microbiota influences gastrointestinal motility and gut-brain communication.
• Compositional changes in gut microbiota have been reported in both conditions.
• Common microbiota characteristics in older adults with constipation and depression have not been systematically studied.

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