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Abstract
The aryl hydrocarbon receptor (AHR) may be a key factor in regulating inflammation related to Parkinson's disease.
- Dysregulation of the gut-brain axis is suggested to play a role in the development of Parkinson's disease.
- Microbiota-derived metabolites are implicated in the activation of AHR, which influences central nervous system inflammation.
- AHR signaling is associated with the suppression of inflammation through anti-inflammatory and immunosuppressive responses.
- Alterations in intestinal flora and decreased AHR activity are linked to Parkinson's disease.
- Targeting the AHR-gut microbiota axis could represent a new therapeutic approach for managing Parkinson's disease.
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