Human behavioral pharmacology of psychedelics

Mar 28, 2022Advances in pharmacology (San Diego, Calif.)

How psychedelics affect human behavior and brain function

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Abstract

Psychedelics like psilocybin, LSD, and DMT are associated with a unique collection of subjective effects and potential therapeutic benefits.

  • Research on psychedelics has increased significantly over the last decade.
  • Classic psychedelics are characterized by complex subjective effects during and after use.
  • Clinical trials indicate that psychedelics may have lasting positive effects on conditions like treatment-resistant depression and alcohol use disorder.
  • The role of context (set and setting) and mystical experience is important in understanding the effects of psychedelics.
  • Further investigation is required to uncover the mechanisms behind behavior change related to psychedelic use.

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