How Different Doses of Psychedelics and MDMA Affect the Body and Mind

Controlled study data on dosing of classic psychedelics and entactogens are scarce.

• Classic psychedelics and entactogens may be developed into medications for conditions like anxiety and depression.
• Identifying proper doses is crucial for the clinical use of these substances in psychotherapy.
• There is significant interest in understanding dose equivalence, dose-response effects, and subjective experiences related to different doses.
• Microdosing of psychedelics has gained popularity, with recent placebo-controlled studies of LSD published.
• The chapter discusses pharmaceutical aspects and personalized dosing, as well as non-drug factors that could influence responses to psychedelics.

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