Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies

Oct 27, 2022Addiction biology

Psychedelic drugs and alcohol use problems: A review of studies in people and animals

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Abstract

Twenty human studies suggest that may help reduce alcohol consumption.

  • A total of 639 publications were identified, with 27 studies included after selection.
  • Human studies indicate promising data for the use of classic psychedelics in reducing alcohol consumption.
  • Methodological concerns exist in several human studies, including low participant numbers and lack of control groups.
  • Preclinical studies on the effect of classic psychedelics on alcohol consumption are limited and present conflicting results.
  • Psilocybin appears to show the most consistent data as a potential treatment for .
  • Further research with improved methodological quality is needed to clarify the effects of classic psychedelics.

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Key numbers

83%
Reduction in Criteria
Percentage of participants reporting cessation of symptoms post-psychedelic use.
27
Included Studies
Total number of studies included in the systematic review.

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