Fortschritte der Neurologie-Psychiatrie

Psychotherapy combined with serotonin-affecting drugs: opportunities and challenges

Updated

Abstract

Substance-assisted psychotherapy with serotonergic psychoactive agents shows potential for treating conditions like PTSD and depression.

  • Evidence suggests that LSD and psilocybin may be effective in treating alcohol and tobacco addiction.
  • Psilocybin is associated with positive outcomes in anxiety and depression among patients with life-threatening illnesses.
  • Studies indicate that psilocybin could benefit individuals with obsessive-compulsive disorder (OCD) and treatment-resistant major depression.
  • MDMA shows promise in addressing posttraumatic stress disorder (PTSD).
  • Overall, findings indicate efficacy and relatively good tolerability for these substances in therapeutic contexts.
  • Further research is necessary to establish the suitability of these substances for treatment-resistant psychiatric disorders.

Simplified

Full Text

Full text is available at the source.

Funding

Competing interests

Disclosure The authors report no conflicts of interest in this work.
PubMed

What Lands in Your Inbox Each Week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free