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Abstract
Injectable materials like hydrogels could enhance drug delivery for knee osteoarthritis treatment.
- Intra-articular injection is an emerging method for treating knee osteoarthritis that aims to reduce systemic toxicity.
- Traditional oral drugs lack sustained release when delivered via intra-articular injection.
- Hydrogels and hydrogel microspheres are being studied for their potential in maximizing local drug effects and prolonging retention time.
- The review summarizes various hydrogel types and their characteristics, as well as the types of drugs, proteins, and cells used in these delivery systems.
- There is a potential for novel hydrogel-based systems to improve treatment outcomes for knee osteoarthritis.
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