High uric acid levels in shift workers at a Spanish chemical factory

Shift workers demonstrated 2.25 times higher prevalence of hyperuricemia compared to non-shift workers.

• Shift workers engaged in significantly less physical activity (OR=0.22; 95% CI=0.14-0.35; p<0.001).
• They had lower levels of HDL cholesterol (OR=2.1; 95% CI=1.2-3.8; p<0.05).
• There was a higher rate of hypertriglyceridemia among shift workers (OR=2.05; 95% CI=1.3-3.2; p<0.01).
• In adjusted analysis, only the prevalence of hyperuricemia remained significantly higher in shift workers (OR=2.25; 95% CI=1.1-4.6; p<0.05).
• No association was found between shift work and increased smoking or overall cardiovascular risk.

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