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Immunomodulation of human macrophages and myeloid cells by 2-substituted (1–3)-β-d-glucan from P. parvulus 2.6
How a modified sugar from P. parvulus 2.6 affects human immune cells called macrophages and myeloid cells
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Abstract
Purified 2-substituted (1-3)-β-D-glucan activates macrophages and exhibits an anti-inflammatory effect.
- Macrophages are immune cells that play a crucial role in the body's response to pathogens.
- The study focused on the effects of β-glucans produced by specific microorganisms on macrophage activity.
- PMA-differentiated THP-1 cells and M1 pro-inflammatory monocyte-derived macrophages were used to assess these effects.
- The findings suggest that this particular β-D-glucan could enhance macrophage activation.
- An anti-inflammatory response was observed in macrophages treated with the β-D-glucan.
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