Imaging brain chemical signals in the side brain regions using fast magnetic resonance

Significantly higher concentrations of myoinositol and choline were found in the anterior mesial temporal lobe.

• Short echo times (30 ms) and long repetition times (3000 ms) were used to improve MRSI data quality.
• Consistently good-quality data from both temporal lobes could not be obtained due to inhomogeneity and spectral distortions.
• No significant left-right differences in metabolite content were observed in a series of 10 controls.
• Lower concentrations of creatine, glutamate/glutamine, and myoinositol were found in the posterior mesial temporal lobe compared to the posterior lateral temporal lobe.
• The pattern of metabolite concentrations between the lateral and mesial temporal lobes was similar to grey/white matter differences seen in other brain regions.

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