Effect of increased fat availability on metabolism and exercise capacity

Sep 10, 2002Medicine and science in sports and exercise

How More Fat Available Affects Metabolism and Exercise Ability

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Abstract

Ingestion of long-chain triglyceride solutions or intravenous intralipid can reduce whole-body carbohydrate oxidation by significant amounts during exercise.

  • Significant reductions in muscle glycogen utilization were observed during both moderate and intense dynamic exercise lasting 15-60 minutes.
  • Increased fatty acid delivery may lead to substantial muscle glycogen sparing, with reductions ranging from 15-48% compared to control.
  • The impact of elevated fatty acid provision on muscle glucose uptake during exercise remains unclear.
  • Exercise capacity does not consistently improve despite increased availability of fatty acids.

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