Injectable, Intrinsically Antibacterial Conductive Hydrogels with Self-Healing and pH Stimulus Responsiveness for Epidermal Sensors and Wound Healing

Nov 2, 2021ACS applied materials & interfaces

Injectable antibacterial conductive gels that heal themselves and respond to pH for skin sensors and wound healing

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Abstract

An injectable, self-healing, conductive chitosan-based hydrogel demonstrates real-time health monitoring and promotes wound healing.

  • The hydrogel exhibits pH responsiveness, allowing it to transition between liquid and gel states based on acidity levels.
  • It shows self-healing properties, enabling it to recover from damage autonomously.
  • Broad-spectrum antibacterial properties are present without the need for additional antibacterial agents.
  • Biocompatibility tests confirm the hydrogel's suitability for use in medical applications.
  • In a mouse model, the hydrogel significantly enhances wound healing outcomes.
  • The hydrogel functions as an epidermal sensor, capable of real-time monitoring of various human activities.

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