FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Eating During Active Times Causes Insulin Rhythms That Help Muscle Growth by Aligning Energy Supply and Cell Growth Cycles

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

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Abstract

Day-restricted feeding disrupted insulin rhythm, while night-restricted feeding enhanced insulin rhythm and promoted skeletal muscle growth.

  • Eating during the inactive period may disrupt metabolic rhythms in skeletal muscle.
  • Nocturnal rabbits experienced altered insulin rhythms based on feeding timing.
  • Night-restricted feeding is associated with enhanced skeletal muscle growth.
  • Analysis revealed enrichment of circadian rhythm and pancreatic secretion pathways in muscle tissue.
  • Rhythmic insulin may synchronize mitochondrial energy production with cell cycle progression, promoting muscle cell growth.

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