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Rhythmic Insulin Induced by Eating During the Active Phase Promotes Skeletal Muscle Growth via Synchronizing Mitochondrial Energy Supply Rhythm and Cell Cycle
Eating During Active Times Causes Insulin Rhythms That Help Muscle Growth by Aligning Energy Supply and Cell Growth Cycles
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Abstract
Day-restricted feeding disrupted insulin rhythm, while night-restricted feeding enhanced insulin rhythm and promoted skeletal muscle growth.
- Eating during the inactive period may disrupt metabolic rhythms in skeletal muscle.
- Nocturnal rabbits experienced altered insulin rhythms based on feeding timing.
- Night-restricted feeding is associated with enhanced skeletal muscle growth.
- Analysis revealed enrichment of circadian rhythm and pancreatic secretion pathways in muscle tissue.
- Rhythmic insulin may synchronize mitochondrial energy production with cell cycle progression, promoting muscle cell growth.
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