The Efficacy of Intense Pulsed Light Combined With Meibomian Gland Expression for the Treatment of Dry Eye Disease Due to Meibomian Gland Dysfunction: A Multicenter, Randomized Controlled Trial

May 27, 2020Eye & contact lens

Intense Pulsed Light and Gland Massage for Treating Dry Eye from Oil Gland Problems: A Large Controlled Trial

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Abstract

increased by 2.3±1.9 seconds in the intense pulsed light (IPL) treatment group compared to 0.5±1.4 seconds in the control group.

  • Both treatment methods resulted in improvements in dry eye disease (DED) symptoms.
  • The IPL arm showed a greater reduction in symptom severity, with a 38% reduction in SPEED compared to 22% in the control arm.
  • improved by 197% in the IPL arm versus a 96% improvement in the control arm.
  • Corneal fluorescein staining decreased significantly in both groups, but the difference was not statistically significant.
  • A composite score of lid margin abnormalities improved more in the IPL arm, indicating better overall treatment efficacy.

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Key numbers

2.3±1.9 sec
Increase in
increased from baseline to follow-up in the IPL arm.
38%
Decrease in
Percentage change from baseline to follow-up in the IPL arm.
197%
Improvement in
Percentage change in from baseline to follow-up in the IPL arm.

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