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Intermittent or continuous feeding: any difference during the first week?
Differences between intermittent and continuous feeding in the first week
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Abstract
Intermittent feeding may activate autophagy, a process that clears intracellular damage.
- Less aggressive nutrient administration is clinically superior in acute critical illness.
- Nutrient restriction is associated with the activation of autophagy.
- Intermittent feeding is theorized to preserve circadian rhythm and increase protein synthesis.
- Current guidelines advise against intermittent feeding due to lack of demonstrated benefits and increased risk of diarrhea.
- Research on intermittent feeding in the ICU mainly focuses on gastrointestinal complications.
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