Using social routines and relationships to improve depression and prevent relapse in bipolar disorder

Interpersonal and social rhythm therapy (IPSRT) targets major pathways to recurrence in bipolar disorder.

• IPSRT addresses medication nonadherence, stressful life events, and disruptions in social rhythms.
• Efficacy of IPSRT has been supported by two large studies when combined with pharmacotherapy.
• IPSRT serves as both an acute intervention and a preventive treatment for bipolar depression.
• The therapy consists of four phases, each with specific focus and duration.
• IPSRT is described as a modular treatment, allowing for flexibility in application.

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