Inulin may improve blood vessel-related thinking problems by restoring inhibitory brain signals through gut bacteria and their chemical messengers

Prebiotics may improve cognitive function in the medial prefrontal cortex (mPFC) related to vascular cognitive impairment (VCI).

• Vascular cognitive impairment (VCI) negatively impacts the functioning of the medial prefrontal cortex (mPFC).
• The mPFC's function relies on proper GABA transmission, which could be disrupted in VCI.
• Prebiotics like inulin are being explored for their potential to modify gut microbiota.
• It remains unclear how prebiotics may restore GABAergic function in the mPFC through the gut-brain connection.

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