Treating Stroke by Changing the Adult Brain Stem Cell Environment Using the Wnt/β-catenin Pathway

Ischemic stroke accounts for approximately 80% of stroke cases globally.

• Ischemic stroke results from the blockage of blood vessels in the brain.
• Enhancing the generation of new neurons may help replace damaged cells in the brain after a stroke.
• The Wnt/β-catenin pathway has been shown to promote the creation of new neurons following brain injury.
• Targeting the Wnt/β-catenin pathway could be a beneficial strategy for treating ischemic stroke and related neurological conditions.
• This review discusses the role of the Wnt/β-catenin pathway in neurogenesis as a potential therapeutic approach.

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