Comes a time

Up to 90% of the transcriptome in Arabidopsis seedlings cycles in at least one environmental condition.

• The circadian clock in Arabidopsis operates on a roughly 24-hour cycle and consists of complex feedback loops involving various regulatory mechanisms.
• Widespread clock control influences both the transcriptome and metabolome, although changes in metabolite levels are less pronounced than those in transcripts.
• Enzyme activities and metabolites show diurnal fluctuations that are connected to the circadian clock.
• Certain metabolites, including organic nitrogen intermediates, can influence the functioning of the circadian clock, suggesting a link between metabolic signals and clock regulation.

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