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Abstract
The study investigated the neuroprotective potential of short-chain fatty acids produced by Lactiplantibacillus plantarum C10 in a rotenone-induced Parkinson's disease zebrafish model.
- Parkinson's disease is associated with dopaminergic neuronal degeneration, oxidative stress, and neuroinflammation.
- Evidence suggests that the gut-brain axis may influence neuroinflammation and disease progression.
- Probiotic-derived short-chain fatty acids could have a role in modulating these effects.
- The rotenone-induced zebrafish model serves as a relevant system for studying neuroprotective agents in Parkinson's disease.
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