Critical reviews in oncology/hematology

How Location, Season, and Body Clock May Affect Outcomes of Cancer Treatments Using Chemotherapy, Immunotherapy, or Both

Updated

Abstract

Evaluation of treatment timing, seasonality, latitude, and vitamin D status is associated with efficacy and toxicity outcomes in systemic therapy for solid tumors.

  • Treatment timing may influence the effectiveness and side effects of systemic therapy.
  • Seasonal variations could play a role in how well treatments work.
  • Geographic latitude may be linked to treatment outcomes in patients.
  • Vitamin D status might be related to both efficacy and toxicity in cancer therapy.

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