Atherosclerosis

How lowering LDL cholesterol affects heart risk over time: A combined analysis of 60 clinical trials

Updated

Abstract

The effects of LDL-C reduction on cardiovascular risk over time remain uncertain.

  • Long-term treatment with LDL-C lowering therapies is common for individuals with or at high risk of cardiovascular disease.
  • The stability of LDL-C reduction effects on cardiovascular risk over time is not well established.
  • Further investigation is needed to assess how LDL-C reduction impacts cardiovascular risk longitudinally.

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