Lancet (London, England)

Lowering LDL cholesterol with statins in people at low risk of heart and blood vessel disease: combined analysis of 27 clinical trials

Updated

Abstract

Statins reduce LDL cholesterol and may prevent vascular events.

  • The effectiveness of statins in individuals at low risk for vascular events is not clearly established.
  • There is uncertainty regarding the overall benefits of statin therapy for this population.
  • While statins are known to lower LDL cholesterol, their impact on long-term health outcomes in low-risk individuals is still being evaluated.

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