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Time Sequence of Lipogenic Changes in Adipose Tissue of Rats when Converted from Ad Libitum Feeding to Meal-Eating
Timing of fat-making changes in rat fat tissue when switching from free eating to scheduled meals
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Abstract
Meal-fed rats showed greater glycogen levels in adipose tissue compared to nibblers.
- Lipogenic enzyme activities in meal-fed rats were decreased or unchanged during the first 10 days.
- In vitro and in vivo rates of fatty acid synthesis progressively increased in meal-fed rats over the same period.
- The higher glycogen levels in meal-fed rats suggest altered substrate uptake or enzyme activation in adipose tissue.
- The initial increase in fatty acid synthesis may not be due to the quantity of enzymes present.
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