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Metabolic Responses of Zucker Fatty and Lean Rats Fed Carbohydrate Diets Ad Libitum or in Meals
Metabolic responses in fatty and lean rats eating carbohydrate diets freely or in scheduled meals
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Abstract
Feeding young male Zucker rats diets containing 54% carbohydrates for 4 weeks demonstrated significant metabolic differences associated with genotype and feeding patterns.
- Genotype effects on liver and adipose tissue enzyme activities were observed, differing between fatty and lean rats.
- Food intake and liver size differences were noted only in meal-fed rats, while body weight gain differences occurred only in ad libitum-fed rats.
- Sucrose consumption influenced food efficiency and body weight gain, along with liver enzyme activities and fat pad size, across both feeding patterns.
- The impact of sucrose compared to starch was evident in liver enzyme activities and soluble adipose tissue protein levels in both feeding conditions.
- The disaccharide comparison revealed greater effects of sucrose over invert sugar in liver enzyme activities and fat pad size in ad libitum-fed lean rats.
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