Nature reviews. Nephrology

How Long COVID may affect kidney function

Updated

Abstract

COVID-19 may lead to long-term kidney issues, including chronic kidney disease (CKD).

  • Long COVID is defined by ongoing symptoms or effects lasting at least 3 months after infection with SARS-CoV-2.
  • COVID-19 can cause acute kidney injury and may increase the risk of developing chronic kidney disease.
  • Patients with chronic kidney disease may face a higher risk of severe COVID-19 and long COVID.
  • COVID-19 has been linked to a specific kidney condition known as COVID-19-associated nephropathy.
  • Vaccination against SARS-CoV-2 may lower the risk of COVID-19 and long COVID, especially for those with CKD.
  • Long-term follow-up of COVID-19 patients could help identify those at risk for chronic kidney disease.

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Full Text

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Funding

Competing interests

Competing interests: U.A. reports no competing interests; V.I. has received a Long-term Fellowship grant from the European Renal Association (ERA) and is an Editorial Board member of NDT; S.B. reports consultancy fees from AstraZeneca, Bayer and GSK; A.K. reports consulting fees from Amgen, AstraZeneca, Boehringer Ingelheim, CSL Vifor, Delta4, GlaxoSmithKline, Novartis, Otsuka, Roche and Walden Biosciences, all outside of the submitted work. A.K. serves as an Associate Editor of Glomerular Diseases and an Editor of NDT. M.J.S. reports personal fees from NovoNordisk, Jansen, Mundipharma, AstraZeneca, Esteve, Fresenius, Ingelheim Lilly, Vifor and ICU, and grants and personal fees from Boehringer Ingelheim; A.B. received consultancy fees from Amgen, AstraZeneca, Boehringer Ingelheim, CSL Vifor, Otsuka and Sobi and payment or honoraria for lectures, presentations, speaker’s bureaus, manuscript writing or educational events from AstraZeneca, Bayer, Boehringer Ingelheim, ChemoCentryx, CSL Vifor, Fresenius, GlaxoSmithKline and Otsuka; A.B. is an Editorial Board member of CKJ.
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