JAMA network open

Ongoing Long COVID Symptoms and Monitoring Gaps at 58 US Hospitals

Updated

Abstract

In a cohort of 457,950 COVID-19 cases, 16.28% were identified as having postacute sequelae of SARS-CoV-2 infection (PASC).

  • The P2RC algorithm identified 74,560 PASC cases, more than double the rate captured by existing diagnostic codes (<7%).
  • Among the identified PASC cases, 89.31% developed chronic conditions requiring ongoing clinical management, representing 14.54% of the total COVID-19 cohort.
  • Of the 883 diagnostic codes associated with PASC, 67.27% were classified as chronic or potentially chronic conditions.
  • Significant organ system heterogeneity was observed, with different regions showing distinct patterns of chronic conditions.
  • The prevalence of PASC is projected to increase through mid-2024, indicating a growing healthcare burden.

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