Loop Duodenojejunal Bypass with Sleeve Gastrectomy: Comparative Study with Roux-en-Y Gastric Bypass in Type 2 Diabetic Patients with a BMI <35 kg/m2, First Year Results

Sixty patients with type 2 diabetes and a body mass index under 35 kg/m² participated in a comparison of two surgical techniques over one year.

• Operative time and length of hospital stay were significantly longer for the loop duodenojejunal bypass with sleeve gastrectomy group compared to the Roux-en-Y gastric bypass group.
• No statistical differences were found between the two groups in mean BMI, fasting plasma glucose, or %HbA1c at baseline or one year, although these parameters significantly decreased from preoperative values.
• The level of beta-cell function, measured by HOMA-%B, was significantly higher in the loop duodenojejunal bypass with sleeve gastrectomy group at one year.
• Resolution of comorbidities was similar between the two surgical techniques.
• Late complications appeared to be higher in the Roux-en-Y gastric bypass group, with 12 complications compared to 5 in the loop duodenojejunal bypass with sleeve gastrectomy group.

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