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M1 Intrinsically Photosensitive Retinal Ganglion Cells Integrate Rod and Melanopsin Inputs to Signal in Low Light
Light-sensitive retinal cells combine rod and melanopsin signals to detect dim light
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Abstract
M1 ipRGCs exhibit a wide spectrum of responses to dim light driven by both rod signals and melanopsin.
- M1 ipRGCs integrate rod and melanopsin signals to respond to low light.
- Responses to dim light vary significantly among M1 ipRGCs.
- Rod input is associated with larger and more complex dendritic structures in M1 ipRGCs.
- Melanopsin contributes notably to the light responses of M1 ipRGCs under very low light conditions.
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