Light-sensitive retinal cells combine rod and melanopsin signals to detect dim light

M1 ipRGCs exhibit a wide spectrum of responses to dim light driven by both rod signals and melanopsin.

• M1 ipRGCs integrate rod and melanopsin signals to respond to low light.
• Responses to dim light vary significantly among M1 ipRGCs.
• Rod input is associated with larger and more complex dendritic structures in M1 ipRGCs.
• Melanopsin contributes notably to the light responses of M1 ipRGCs under very low light conditions.

Simplified