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Abstract
Major Depressive Disorder (MDD) is associated with an imbalance of gut bacteria, including a decrease in anti-inflammatory butyrate-producing types.
- The gut-brain axis may influence MDD through various metabolites.
- Gamma-Aminobutyric Acid (GABA) and Quinolinate are among the metabolites of interest.
- These metabolites could affect the balance of excitatory and inhibitory signals in the brain.
- MDD is characterized by an increase in hyperinflammatory bacteria.
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