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Abstract
Mathematical models of circadian rhythms aim to enhance understanding and prediction of biological processes impacted by these ~24-hour cycles.
- Circadian rhythms influence various biological processes, including body temperature, sleep/wake cycles, and disease susceptibility.
- Individual cells contain circadian clocks, which interact to form emergent properties at tissue and organism levels.
- Mathematical models can manipulate circadian systems in a cost-effective manner, surpassing traditional experimental methods.
- These models help resolve contradictory empirical results and generate new hypotheses and experimental designs.
- Different models vary in structure, assumptions, parameters, and constraints, reflecting the complexity of circadian rhythms across species.
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