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Effect of Meal-feeding on the Daily Variations of Insulin, Glucose, and NADP-linked Dehydrogenases in Rats
How scheduled meals affect daily changes in insulin, blood sugar, and energy-related enzymes in rats
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Abstract
Ad libitum-fed rats exhibited synchronized daily rhythms in insulin and glucose levels after consuming a 66.5% glucose diet for 1 to 3 weeks.
- Daily rhythms in insulin and glucose levels were observed in ad libitum-fed normal rats.
- These rhythms were shifted in timing during a 2-hour feeding period in the late morning.
- Adrenalectomized rats showed different rhythm patterns compared to nonadrenalectomized rats.
- Timing of food intake may influence observed rhythms rather than meal-feeding alone.
- The presence of adrenal glands appears to play a role in maintaining these rhythms.
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