Mediation analysis of chronotype, sleep-related factors, and depressive symptoms among workers: a cross-sectional study

Dec 27, 2023Annals of occupational and environmental medicine

How Sleep Patterns and Timing May Link to Depression Symptoms in Workers

AI simplified

Circadian Biology on OpenScience ↗PubMed ↗DOI ↗OA ↗

Abstract

Evening are associated with an increased risk of depressive symptoms, with an odds ratio of 2.96.

Only 1.8% of participants identified as evening chronotypes, while 93.5% were intermediate and 4.7% morning types.
Insomnia severity, sleep quality, and pre-sleep cognitive arousal partially mediated the relationship between chronotype and depressive symptoms.
Insomnia severity accounted for 28.44% of the mediation effect, sleep quality for 31.25%, and cognitive arousal for 23.58%.
Social jetlag did not significantly mediate the relationship between chronotype and depressive symptoms.

AI simplified

BACKGROUND: This study aimed to examine the impact of on depressive symptoms and explore the mediating effects of sleep quality, pre-sleep cognitive arousal, and social jetlag in a sample of wage earners.

METHODS: A total of 3,917 waged workers were surveyed online in July 2022. Logistic regression and mediation analysis were used to assess the relationship between chronotype (morningness, intermediate, and eveningness) and depressive symptoms (Patient Health Questionnaire ≥ 5), and the mediating effects of (ISI), (PSQI), and Pre-Sleep Arousal Scale (PSAS). All analyses were adjusted for age, education level, income level, marital status, coffee consumption, alcohol consumption, physical activity, occupation, employment status, and working hours to calculate odds ratios (ORs).

RESULTS: The chronotypes of all the participants were divided into morningness (4.7%), intermediate (93.5%), and eveningness (1.8%). Multiple logistic regression analysis showed an increased risk of depression in the eveningness chronotype (OR: 2.96; 95% confidence interval [CI]: 1.51, 5.86). Regarding the mediation analysis, ISI mediated 28.44% (95% CI: 16.39-40.5), PSQI for 31.25% (95% CI: 19.36, 43.15), and PSAS-Cognitive Score (PSAS-C) for 23.58% (95% CI: 10.66, 36.50) of the association between chronotype and depressive symptoms. However, social jetlag did not significantly mediate this relationship. (percentage mediated = 0.75%, 95% CI: -3.88, 5.39).

CONCLUSIONS: Evening chronotypes exhibit an increased risk of depressive symptoms, which ISI, PSQI, and PSAS-C partially mediated. This suggests that interventions to improve sleep quality and maintain adequate sleep habits may effectively prevent and treat depression in employees with an eveningness chronotype.

Key numbers

2.96

Increased Risk of Depression

Odds ratio for evening vs. morning

28.44%

Mediation by

Percentage mediated by

31.25%

Mediation by

Percentage mediated by

Full Text

We can’t show the full text here under this license. Use the link below to read it at the source.

View full text (PDF) ↗View full text ↗

Mediation analysis of chronotype, sleep-related factors, and depressive symptoms among workers: a cross-sectional study

Abstract

Key numbers

Full Text

You found one interesting study. We’ll send the next 7.

what lands in your inbox each week:

Recent issues from the circadian biology brief

Abstract

Key numbers

Full Text

Related papers

You found one interesting study. We’ll send the next 7.

what lands in your inbox each week:

Recent issues from the circadian biology brief