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Relationship between melanin-concentrating hormone- and neuropeptide Y-containing neurons in the goldfish hypothalamus
How two types of brain cells that control feeding interact in the goldfish hypothalamus
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Abstract
Intracerebroventricular administration of melanin-concentrating hormone inhibits food intake in goldfish.
- MCH and NPY-like signals are found throughout the goldfish brain.
- MCH-containing nerve fibers are in close proximity to NPY-containing neurons in the nucleus posterioris periventricularis.
- These findings indicate a direct connection between MCH and NPY neurons in goldfish.
- MCH may act as an anorexigenic neuropeptide, reducing the feeding-promoting effects of NPY.
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