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Abstract
Four weeks of bright light exposure is associated with increased volume of the left dentate gyrus in patients with mood disorders.
- Bright light therapy may be an effective treatment for mood disorders.
- The volume increase in the left dentate gyrus could be influenced by genetic variation in the OPN4 gene.
- Specifically, the variant rs1079610 in the OPN4 gene may play a role in this light-induced volumetric change.
- This hypothesis is based on exploratory observations rather than definitive results.
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