Melatonin Does Not Link the Eyes to the Rest of the Circadian System in Quail: A Neural Pathway Is Involved

Jan 1, 1990Journal of biological rhythms

Melatonin does not connect the eyes to the body’s internal clock in quail; a brain pathway is involved

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Abstract

Enucleation disrupts the circadian activity rhythm in Japanese quail, leading to arrhythmicity in constant darkness.

  • Enucleated Japanese quail show disrupted activity patterns under 24-hour light-dark cycles.
  • Many enucleated birds can still maintain entrainment to light-dark cycles despite disruptions.
  • In constant darkness, enucleated birds become arrhythmic, indicating a crucial role of the eyes beyond light detection.
  • The eyes of quail can produce and release melatonin, a hormone involved in timing within the circadian system.
  • Neural communication appears to play a role in circadian rhythm regulation, as optic nerve section mimics the effects of enucleation.

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