BMJ open

Effects of adding melatonin or online sleep therapy versus placebo on depression in young adults with mood disorders: a 12-week trial plan

Updated

Abstract

Sleep and circadian rhythm disturbances are proposed mechanisms in some cases of mood disorders.

  • Sleep and circadian rhythm issues may contribute to depressive and bipolar disorders.
  • The effectiveness of sleep and circadian-based therapies as antidepressants is uncertain.
  • There is a specific focus on young adults aged 18-30 years with mood disorders.

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