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Abstract
The nighttime serum concentration of melatonin shows an incremental change toward the end of pregnancy.
- Melatonin is a hormone produced by the pineal gland that plays a role in regulating biological rhythms.
- This small molecule crosses the placenta easily, providing essential information about light and dark cycles to the fetus.
- Melatonin may function as a circadian rhythm modulator, endocrine modulator, immunomodulator, and antioxidant during pregnancy.
- It appears to be essential for a successful pregnancy and may help address complications such as abortion, pre-eclampsia, and fetal brain damage.
- Current scientific evidence supports a significant role for melatonin in human pregnancy.
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