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Abstract
Obesity is recognized as a systemic determinant of dermatologic disease.
- Excess body fat is linked to insulin resistance and adipose-tissue dysfunction.
- Chronic low-grade inflammation associated with obesity may worsen skin conditions.
- Altered immune responses due to obesity could influence the severity of inflammatory skin disorders.
- Conditions like psoriasis and hidradenitis suppurativa demonstrate the connection between metabolic and skin health.
- The concept of a metabolic-dermatologic axis suggests that fat tissue, metabolism, immune response, and skin inflammation interact with each other.
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