Diabetic medicine : a journal of the British Diabetic Association

Metabolic and kidney outcomes in people with chronic kidney disease, type 2 diabetes, and obesity taking tirzepatide in everyday care

Updated

Abstract

Tirzepatide may offer metabolic and potential kidney protection benefits in patients with advanced chronic kidney disease (CKD).

  • Obesity and type 2 diabetes mellitus are linked to faster progression of chronic kidney disease.
  • Tirzepatide is designed to activate two specific receptors that may help in managing metabolic health.
  • Clinical trials suggest that tirzepatide could provide benefits beyond metabolic improvements, potentially affecting kidney health.
  • Real-world effects of tirzepatide in patients with advanced CKD have not been extensively studied.

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