Gut Microbiome Metabolism and Its Possible Links to Epilepsy

More than 65 million people worldwide are affected by epilepsy, with about 30% developing drug-resistant forms.

• Gut microbial communities may influence central nervous system function through the gut-brain axis.
• Current anti-seizure medications primarily suppress seizures but do not prevent disease progression.
• There is increasing evidence suggesting that microbiota-dependent pathways could modulate seizure activity.
• The mechanisms underlying the interactions between gut microbiota and epilepsy are not fully understood.

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