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Microbial metabolites and immunotherapy: Basic rationale and clinical indications
How Microbial Chemicals Relate to Immunotherapy and When They May Be Used
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Abstract
Microbial metabolites can influence the host immune response during cancer immunotherapy.
- The gut microbiota contributes to host immunity through a variety of metabolic products.
- Microbial metabolites, including short chain fatty acids and purine metabolites, are associated with modulating immune cell behavior.
- Recent studies highlight the role of the microbiome in enhancing the effectiveness of immune checkpoint blockade therapies.
- Understanding how these metabolites interact with immune responses may improve cancer treatment strategies.
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