How gut microbe chemicals and the nerve to the brain help control eating

The gut microbiota may influence energy balance through small molecules that communicate with mammalian receptors.

• Microbial metabolites could regulate food intake by interacting with the host's receptors.
• The exact mechanisms of how gut microbiota affects energy intake and body weight are not fully understood.
• Vagal afferent neurons may play a role in the communication between gut microbes and the brain.
• The review highlights possible beneficial effects of microbial metabolites on food intake regulation.

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