Frontiers in cellular and infection microbiology

How Gut Bacteria and Brain Communication May Influence and Help Treat Frailty

Updated

Abstract

The microbiome-gut-brain axis (MGBA) is associated with frailty syndrome, a significant public health challenge due to global aging.

  • Frailty syndrome is linked to changes in the gut microbiome.
  • The interaction between the gut microbiome and frailty suggests a bidirectional relationship.
  • Potential biological mechanisms underlying the MGBA's role in frailty are being systematically analyzed.
  • Targeting the microbiome may lead to the development of new biomarkers for frailty.
  • Multi-dimensional approaches to regulating the MGBA could promote healthy aging.

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Funding

Competing interests

No commercial or financial ties reported.
PubMed

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