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Microbiome–Gut–Brain Axis: Implications for the Links Between Inflammatory Bowel Disease and Neuropsychiatric Disorders
How Gut Bacteria May Connect Inflammatory Bowel Disease and Brain Disorders
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Abstract
Dysregulation of in activates the gut immune system.
- The gut and brain are interconnected, processing signals from both the environment and internal cues.
- Activation of the gut immune system is associated with dysregulation of gut microbiota in inflammatory bowel disease.
- The may play a role in the development of neuropsychiatric disorders such as autism, depression, and anxiety.
- Molecular mechanisms involved in gut-brain signaling include immune responses, neuroendocrine factors, and microbial composition.
- Specific inflammatory bowel disease is linked to certain microbial genera and various psychiatric and neurological disorders.
- Targeting gut microbiota could potentially offer new treatment approaches for neuropsychiatric disorders influenced by gut interactions.
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Key numbers
50%
Prevalence of Anxiety Symptoms
Among patients with active .
33%
Prevalence of Depression Symptoms
In the same patient population with .
40–60%
Clinical Remission Rates
For clinical remission in patients with .