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Abstract
Essence
Gut microbiome disruption in may connect intestinal inflammation with neuropsychiatric disorders through immune, barrier, microbial, and neuroendocrine pathways.
Evidence
This narrative review discusses preclinical and clinical studies on the microbiome-, inflammatory bowel disease, microbial genera, and psychiatric or neurological disorders.
Caveat
As a review of heterogeneous mechanisms and study types, it proposes therapeutic possibilities rather than testing a specific microbiota treatment.
Simplified