The role of the gut microbiota in neuropsychiatric disorders and therapy

Sep 10, 2025Ageing research reviews

The role of gut bacteria in mental health disorders and their treatment

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Abstract

Over one billion individuals globally are affected by neuropsychiatric disorders such as depression, Alzheimer's disease, and Parkinson's disease.

  • Alterations in the gut microbiota, known as gut microbiota dysbiosis, are associated with the development of various neuropsychiatric disorders.
  • The microbiota-gut-brain axis serves as a communication link between the gut and the brain, potentially influencing neuropsychiatric conditions.
  • Scientific evidence indicates that specific changes in gut microbiota composition may play a role in the onset and progression of neuropsychiatric disorders.
  • Interventions aimed at modifying gut microbiota, such as probiotics and dietary changes, could be explored as potential treatments for these disorders.
  • The review discusses both animal and human studies that highlight the significance of gut microbiota in neuropsychiatric health.

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