Full text is available at the source.
Abstract
Recent studies have linked changes in the microbiome to various neuropsychiatric disorders, including autism and depression.
- The gut microbiome plays a crucial role in the development and functioning of brain systems.
- Bidirectional communication between the gut and brain occurs through several pathways, including neuronal and chemical.
- Metagenome-wide association studies have confirmed variations in the microbiome related to neuropsychiatric disorders in large samples.
- Cohort studies are working to clarify the causal relationship between gut microbiota and neuropsychiatric conditions.
- Research is expanding to include various microbiome-modulating therapies, such as probiotics and fecal microbiota transplantation.
- Despite advancements, many aspects of the microbiota-gut-brain axis in neuropsychiatric disorders remain to be explored.
Simplified